If a client is diagnosed with acetaminophen poisoning, what is the priority intervention?

In the case of acetaminophen poisoning, administering acetylcysteine is the priority intervention because it acts as an antidote. Acetylcysteine works by replenishing glutathione stores in the liver, which are depleted by high levels of acetaminophen. By providing this antidote promptly, it helps to prevent or minimize liver damage, which is critical since acetaminophen toxicity can lead to severe hepatic failure.

While performing gastric lavage, obtaining blood work, and administering intravenous fluids are also important in the overall management of a patient with acetaminophen poisoning, they do not directly address the need to counteract the toxic effects of the acetaminophen itself. Gastric lavage may only be considered in certain situations and is not routinely performed, especially if the patient presents several hours after ingestion. Blood work is important for diagnosis and to assess the severity of poisoning, but it is not a treatment. Intravenous fluids can be helpful for hydration and supporting blood pressure, but they do not mitigate the toxic effects of acetaminophen. Therefore, the immediate administration of acetylcysteine is crucial for effectively treating the poisoning and preventing further complications.